Psychopharmacology Scavenger Hunt Concept Map
References
Auerbach, A. (2024). Dynamics of receptor activation by agonists.
Biophysical Journal
,
123
(14), 1915–1923.
https://doi.org/10.1016/j.bpj.2024.01.003
Berg, K. A., & Clarke, W. P. (2023). Making sense of pharmacology: Inverse agonism and functional selectivity.
International Journal of Neuropsychopharmacology
,
21
(10), 962–977.
https://doi.org/10.1093/ijnp/pyy071
Dutta, S., Selvam, B., Das, A., & Shukla, D. (2022). Mechanistic origin of partial agonism of tetrahydrocannabinol for cannabinoid receptors.
Journal of Biological Chemistry
,
298
(4).
https://doi.org/10.1016/j.jbc.2022.101764
Fatunde, O. A., & Brown, S.-A. (2020). The role of CYP450 drug metabolism in precision cardio-oncology.
International Journal of Molecular Sciences
,
21
(2), 604.
https://doi.org/10.3390/ijms21020604
Gilani, B., & Cassagnol, M. (2023, April 24).
Biochemistry, cytochrome P450
. PubMed; StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK557698/
Heim, B., Peball, M., Krismer, F., Djamshidian, A., & Seppi, K. (2023). Pimavanserin: A truly effective treatment for Parkinson’s disease psychosis? A review of interventions.
Neuropsychiatric Disease and Treatment
,
19
, 1303–1312.
https://doi.org/10.2147/NDT.S371641
Jordan, M. R., & Morrisonponce, D. (2024, May 5).
Naloxone
. Nih.gov; StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK441910/
Kikuchi, T., Maeda, K., Suzuki, M., Hirose, T., Futamura, T., & McQuade, R. D. (2023). Discovery research and development history of the dopamine D2 receptor partial agonists, aripiprazole and brexpiprazole.
Neuropsychopharmacology Reports
,
41
(2), 134–143.
https://doi.org/10.1002/npr2.12180
Le, G. H., Wong, S., Bargiota, S., Jennifer, S., Lo, H. K. Y., Orsini, D., Teopiz, K., Guillien, H., Lim, P. K., & McIntyre, R. S. (2025). Biased agonism in psychopharmacology: An opportunity to improve efficacy and safety of treatments.
CNS Spectrums
, 1–39.
https://doi.org/10.1017/s109285292510045x
Martin, D., & Le, J. K. (2023).
Amphetamine
. PubMed; StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK556103/
McNeil, S. E., & Cogburn, M. (2023).
Risperidone
. Nih.gov; StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK459313/
Rahman, S., & Marwaha, R. (2023). Haloperidol. In
www.ncbi.nlm.nih.gov
. StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK560892/
Sadiq, N. M., Dice, T. J., & Mead, T. (2024, February 20).
Oxycodone
. PubMed; StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK482226/
Siwek, M., Wojtasik-Bakalarz, K., Krupa, A. J., & Chrobak, A. A. (2023). Brexpiprazole—Pharmacologic properties and use in schizophrenia and Mood Disorders.
Brain Sciences
,
13
(3), 397–397.
https://doi.org/10.3390/brainsci13030397
Psychopharmacology Scavenger Hunt Concept Map
RESOURCES
Goldin, D. S. (2023).
Fast facts for psychopharmacology for nurse practitioners
. Springer Publishing.
Chapter 4, “Neurotransmitters Overview” (pp. 38–50)
Stahl, S. M. (2021).
Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications
(5th ed.). Cambridge University Press.
Chapter 3, “Ion Channels as Targets of Psychopharmacological Drug Action” (pp. 51–76)
Drugs.comLinks to an external site.
. (2023). https://www.drugs.com/
Note:
Please use the following resource to check the most up-to-date box warnings, FDA approvals and indications, recommendations for follow-up evaluations. changes, etc.
Simple Nursing Team. (2022, May 2).
How to create a basic nursing concept mapLinks to an external site.
.
NEI Psychopharm. (2022, March 14).
How neurotransmitters are transported: Psychotropic transportersLinks to an external site.
[Video]. YouTube. https://www.youtube.com/watch?v=qcT3XEDKnZc&list=PLYAIFzMMgrFpTVhVqfIyB9tPLT43Ec7In&index=3
NEI Psychopharm. (2016, August 16).
The agonist spectrumLinks to an external site.
[Video]. YouTube. https://www.youtube.com/watch?v=dkbV_PA61bg
Olivier, B. (2021, August 20).
6 ways to use concept mapping your researchLinks to an external site.
[Multimedia]. https://www.researchmasterminds.com/life-and-academia/concept-mapping-in-your-research
Taber, K. S. (n.d.).
Concept mapping as a research techniqueLinks to an external site.
. https://science-education-research.com/research-methodology/research-techniques/concept-mapping-as-a-research-technique/
Psychopharmacology Scavenger Hunt Concept Map
You will find that medications used to treat mental health conditions are agonists across the spectrum. It will be important for you to recognize some of those medications and how they act on a variety of neurochemicals in different ways to treat the symptoms.
In this Assignment, you will “scavenger” the literature as you research the agonist spectrum and key neurotransmitters and pathways targeted in psychopharmacology. You will have the opportunity to apply your knowledge as you create a Concept Map exploring each of the agonist spectrum listed below. Support your answers with evidence-based, peer-reviewed scholarly literature. APA style format title page, citations, and references will apply Psychopharmacology Scavenger Hunt Concept Map.
Note:
You will not set up your Assignment as a paragraph-formatted paper but, instead, as a creative, visually appealing Concept Map.
To prepare for this Assignment:
Review the Learning Resources assigned this week.
Review the Concept Map resources.
Explore the listed agonist spectrum and consider the action and receptor of each:
Agonist
Partial agonist
Antagonist
Inverse agonist
The Assignment
You will submit a concept map exploring the four agonists on the agonist spectrum (agonist, partial agonist, antagonist, and inverse agonist) in which you:
Describe the different characteristics of the four agonists and how each mediates distinct biological activities. Include proposed mechanisms and the receptor it is targeting.
Identify how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication.
Scavenge the literature after describing each agonist on the spectrum for research that is based on the medications in the table below.
Apply the medications to the appropriate agonist on the agonist spectrum in your Concept Map.
Medications
Oxycodone
Brexpiprazole
Haloperidol
Naloxone
Aripiprazole
Amphetamine
Risperidone
Pimavanserin
RUBRIC
Concept map explains the four agonists on the agonist spectrum according to different characteristics and mediation of biological activities. Concept map explains the proposed mechanism and receptor it is targeting. Identifies how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication Psychopharmacology Scavenger Hunt Concept Map.
The eight (8) medications provided in the Assignment list are applied to the appropriate agonist on the agonist spectrum.
The concept map is correctly designed and includes creative visual aids.
Written Expression and Formatting—English writing standards: Correct grammar, mechanics, and proper punctuation
Written Expression and Formatting: The submission contains an APA format for title page, citations, and reference list.
Psychopharmacology Scavenger Hunt Concept Map
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