NURS-6630 Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map

NURS-6630 Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map

Psychopharmacology Scavenger Hunt Concept Map

As you continue to learn about psychopharmacology, you will find that medications used to treat mental health conditions are agonists across the spectrum. It will be important for you to recognize some of those medications and how they act on a variety of neurochemicals in different ways to treat the symptoms.

In this Assignment, you will “scavenger” the literature as you research the agonist spectrum and key neurotransmitters and pathways targeted in psychopharmacology. You will have the opportunity to apply your knowledge as you create a Concept Map exploring each of the agonist spectrum listed below. Support your answers with evidence-based, peer-reviewed scholarly literature. APA style format title page, citations, and references will apply.

Note:
 You will not set up your Assignment as a paragraph-formatted paper but, instead, as a creative, visually appealing Concept Map.

Resources

 

Be sure to review the Learning Resources before completing this activity.

Click the weekly resources link to access the resources.

WEEKLY RESOURCES

To prepare for this Assignment:

Review the Learning Resources assigned this week.

Review the Concept Map resources.

Explore the listed agonist spectrum and consider the action and receptor of each:

Agonist

Partial agonist

Antagonist

Inverse agonist

The Assignment

You will submit a concept map exploring the four agonists on the agonist spectrum (agonist, partial agonist, antagonist, and inverse agonist) in which you:

PLACE YOUR ORDER HERE

Describe the different characteristics of the four agonists and how each mediates distinct biological activities. Include proposed mechanisms and the receptor it is targeting.

NURS-6630
Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map

Identify how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication.

Scavenge the literature after describing each agonist on the spectrum for research that is based on the medications in the table below.

Apply the medications to the appropriate agonist on the agonist spectrum in your Concept Map.

 

Medications

Oxycodone

Brexpiprazole

Haloperidol

Naloxone

Aripiprazole

Amphetamine

Risperidone

Pimavanserin

 

References

Jacobson, K. A., Suresh, R. R., & Oliva, P. (2023). A2A adenosine receptor agonists, antagonists, inverse agonists and partial agonists. In 
International review of neurobiology
 (Vol. 170, pp. 1-27). Academic Press. https://www.sciencedirect.com/science/article/pii/S0074774223000788

Obeng, S., McMahon, L. R., & Ofori, E. (2025). Patent review of novel compounds targeting opioid use disorder (2018-2024). 
Expert Opinion on Therapeutic Patents
, (just-accepted). https://www.tandfonline.com/doi/abs/10.1080/13543776.2024.2446230 NURS-6630 Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map

Pagare, P. P., Flammia, R., & Zhang, Y. (2024). IUPHAR review: Recent progress in the development of Mu opioid receptor modulators to treat opioid use disorders. 
Pharmacological research
, 
199
, 107023. https://www.sciencedirect.com/science/article/pii/S1043661823003791

Peters, K. Z., Cheer, J. F., & Tonini, R. (2021). Modulating the neuromodulators: dopamine, serotonin, and the endocannabinoid system. 
Trends in neurosciences
, 
44
(6), 464-477. https://www.cell.com/trends/neurosciences/abstract/S0166-2236(21)00022-9

Stanley, L. A. (2024). Drug metabolism. In 
Pharmacognosy
 (pp. 597-624). Academic Press. https://www.sciencedirect.com/science/article/pii/B9780443186578000293

Zhang, Y., Liang, X., Bao, X., Xiao, W., & Chen, G. (2022). Toll-like receptor 4 (TLR4) inhibitors: Current research and prospective. 
European journal of medicinal chemistry
, 
235
, 114291. https://www.sciencedirect.com/science/article/pii/S0223523422001933 NURS-6630 Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map

 

NURS-6630 Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map Rubric

NURS_6630_Week2_Assignment_Rubric

Criteria

Ratings

Pts

This criterion is linked to a Learning Outcome
Concept map explains the four agonists on the agonist spectrum according to different characteristics and mediation of biological activities. Concept map explains the proposed mechanism and receptor it is targeting. Identifies how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication.

50
 
to >
36.0
 pts
Excellent
The response comprehensively and clearly explains each of the four agonists on the agonist spectrum according to different characteristics and mediation of biological activities. Identifies how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication. The response comprehensively and clearly explains the proposed mechanism and receptor it is targeting.

36
 
to >
24.0
 pts
Good
The response clearly explains each of the four agonists on the agonist spectrum but is not comprehensive according to different characteristics and mediation of biological activities. . Identifies how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication; but is not comprehensive. The response clearly explains the proposed mechanism and receptor it is targeting but is not comprehensive.

24
 
to >
11.0
 pts
Fair
The response inaccurately or vaguely explains each of the four agonists on the agonist spectrum or only discusses three out of the four agonists. The response inaccurately or vaguely explains the proposed mechanism and/or receptor it is targeting. Vaguely or inaccurately identifies how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication.

11
 
to >
0
 pts
Poor
The response inaccurately or vaguely explains two out of four agonists on the agonist spectrum, or the response is missing. The response includes inaccurate and vague examples that do not explain the proposed mechanism and receptor it is targeting, or it is missing. Does not identify how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication.

50
 pts

This criterion is linked to a Learning Outcome
The eight (8) medications provided in the Assignment list are applied to the appropriate agonist on the agonist spectrum.

30
 
to >
21.0
 pts
Excellent
All eight (8) of the medications are accurately applied to the correct agonist on the agonist spectrum.

21
 
to >
12.0
 pts
Good
Six to seven (6–7) of the medications are accurately applied to the correct agonist on the agonist spectrum.

12
 
to >
6.0
 pts
Fair
Four to five (4–5) of the medications are accurately applied to the correct agonist on the agonist spectrum.

6
 
to >
0
 pts
Poor
Less than three (3) of the medications are accurately applied to the correct agonist on the agonist spectrum.

30
 pts

This criterion is linked to a Learning Outcome
The concept map is correctly designed and includes creative visual aids.

10
 
to >
7.0
 pts
Excellent
The concept map accurately portrays a concept map design and includes two (2) or more creative visual aids.

7
 
to >
4.0
 pts
Good
The concept map accurately portrays a concept map design and includes less than two (2) creative visual aids.

4
 
to >
1.0
 pts
Fair
The concept map accurately portrays a concept map design with no inclusion of creative and visual aids.

1
 
to >
0
 pts
Poor
The submission does not accurately portray a concept map design.

10
 pts

This criterion is linked to a Learning Outcome
Written Expression and Formatting—English writing standards: Correct grammar, mechanics, and proper punctuation

5
 
to >
4.0
 pts
Excellent
Uses correct grammar, spelling, and punctuation with no errors.

4
 
to >
3.0
 pts
Good
Contains a few (one or two) grammar, spelling, and punctuation errors.

3
 
to >
1.0
 pts
Fair
Contains several (three or four) grammar, spelling, and punctuation errors.

1
 
to >
0
 pts
Poor
Contains many (five or more) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.

5
 pts

This criterion is linked to a Learning Outcome
Written Expression and Formatting: The submission contains an APA format for title page, citations, and reference list.

5
 
to >
4.0
 pts
Excellent
Uses correct APA format for title page, citations, and reference list with no errors.

4
 
to >
3.0
 pts
Good
Contains one or two APA format errors with title page, citations, and reference list.

3
 
to >
1.0
 pts
Fair
Contains three or four APA format errors with title page, citations, and reference list.

1
 
to >
0
 pts
Poor
Missing APA format title page, citations, and/or reference list.

5
 pts

Total Points: 
100 NURS-6630 Week 2: Assignment Psychopharmacology Scavenger Hunt Concept Map